Unraveling The Microscopic Architecture Of Skeletal Muscle: How Myofilament Arrangement Drives Contraction
The striations of skeletal muscle cells are produced by the precise arrangement of myofilaments, the protein filaments that generate force for muscle contraction. Myosin filaments, composed of thick filaments, bind to actin filaments, composed of thin filaments. This interaction forms the cross-bridges responsible for muscle contraction. The regular arrangement of these filaments creates alternating light…