Troponin: Unlocking Muscle Contraction Through Tropomyosin Regulation
Troponin, part of the troponin complex on thin filaments in muscles, facilitates cross bridge formation by regulating the position of tropomyosin. In the absence of calcium, tropomyosin covers myosin-binding sites on actin, preventing cross bridge formation. When calcium binds to troponin, it undergoes a conformational change, shifting tropomyosin and exposing these sites. Myosin heads can…